2024 Cenpf cancer

Cenpf cancer

Author: fpkn

August undefined, 2024

WebFeb 21, 2024 · As confirmed by the Tumor Immune Estimation Resource, we found highly expressed centromere protein F (CENPF) in SKCM and its metastases. Immunostaining of human melanoma tissues demonstrated high CENPF expression. WebFeb 7, 2024 · MiR-1-3p targets CENPF to repress tumor-relevant functions of gastric cancer cells. Zhou S, Han H, Yang L, Lin HZhou S, et al. BMC Gastroenterol, 2024 Mar 28. …

Anti-CENPF antibody (ab84697) Abcam

WebCentromere protein F is a protein that in humans is encoded by the CENPF gene. [5] [6] [7] It is involved in chromosome segregation during cell division. It also has a role in the orientation of microtubules to form cellular cilia. [8] [9] Function [ edit] WebJan 24, 2024 · Based on these genes, we constructed and validated a 5-gene prognostic signature (including ACADM, CENPF, KDELC1, PLOD2, and TRMT1) to distinguish low- and high-risk KIRC patients of poor survival in TCGA and E-MTAB-1980 cohorts. indian groceries near lake nona

1063 - Gene ResultCENPF centromere protein F [ (human)]

WebCentromere protein F is a protein that in humans is encoded by the CENPF gene. [5] [6] [7] It is involved in chromosome segregation during cell division. It also has a role in the … WebOct 6, 2024 · Cervical cancer (CC) is the fourth most common female malignancy worldwide. More than half a million women are diagnosed with cervical cancer and the … WebOct 11, 2024 · The role of CENPF in breast cancer (BC) bone metastasis remains unclear. Methods Using the ONCOMINE database, we compared the expression of CENPF in breast cancer and normal tissues. Findings were confirmed in 60 BC patients through immunohistochemical (IHC) staining. localsharenj

CENPF promotes papillary thyroid cancer progression by …

Frontiers A Novel Prognostic Signature for Survival Prediction and ...

WebMar 20, 2024 · Among CENP family genes, CENPF and CENPE are mutated at high frequencies in various tumors, while CENPM and CENPA are less frequently mutated. Furthermore, CENPs regulate the tumor mutational burden, stemness, and microsatellite instability, and are associated with tumor immunity. WebMar 21, 2024 · The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or … local shanghai time local shampoo brands in philippines

"WebJul 9, 2024 · CENPF protein has a broad expression in multiple tissues, such as the testis, bone marrow and lymph node . CENPF is also highly expressed in several types of human tumors, such as breast cancer, pancreatic carcinoma and prostate cancer and has been identified as a protein marker for tumor cell proliferation (9,10). To the best of our … " - Cenpf cancer

Cenpf cancer

CENPA is one of the potential key genes associated with …

WebOct 6, 2024 · TOP2A and CENPF are a synergistic pair of MRs that are overexpressed and activated in CC. Their high expression is correlated with some prognosis features (e.g. metastasis) and molecular features (e.g. somatic mutations) and distinctly high in CC vs. many other cancer types. They may be good biomarkers and anticancer drug targets for … WebCENPF, CENPE, CENPU, CENPA, and CENPM were the most commonly reported CENPs in breast cancer datasets. Figure 2 The mRNA expression levels of CENPs in different …

Did you know?

WebJan 1, 2024 · CENPF is identified upregulation in pancreatic cancer by genomics profile. • High expression of CENPF is correlated with poor prognosis of patients. • Silencing CENPF significantly inhibited PC cell proliferation, migration and EMT. • Silencing CENPF caused cell cycle arrest and tumorigenicity of pancreatic cells. WebApr 10, 2024 · In particular, CENPF overexpression is significantly associated with tumor metastasis and poor prognosis of hepatocellular carcinoma or breast cancer patients [15,16]. In addition, CENPF was also found to be remarkably upregulated in pancreatic cancer, non-small cell lung cancer and papillary thyroid cancer and is commonly …

Web(A) CENPA is more highly expressed in ovarian cancer tissues than in normal tissues (*P<0.05). (B) CENPF is more highly expressed in ovarian cancer tissues than in normal … WebFeb 7, 2024 · MiR-1-3p targets CENPF to repress tumor-relevant functions of gastric cancer cells. Zhou S, Han H, Yang L, Lin HZhou S, et al. BMC Gastroenterol, 2024 Mar 28. PMID 35346060 CENPF as an independent prognostic and metastasis biomarker corresponding to CD4+ memory T cells in cutaneous melanoma.

WebFeb 28, 2024 · • CENPF is a potential oncogene and prognostic marker in RCC, which can be used as an independent prognostic factor. Introduction Other Section Renal cell carcinoma (RCC) is the ninth most common cancer worldwide. It is estimated that there were more than 337,000 new cases diagnosed in 2012. WebProduct name Anti-CENPF antibody See all CENPF primary antibodies Description Rabbit polyclonal to CENPF Host species Rabbit Tested applications Suitable for: IHC-P more details Species reactivity Reacts with: Human Predicted to work with: Chimpanzee, Gorilla, Orangutan Immunogen Synthetic peptide:

WebFeb 21, 2024 · CENPF was shown to promote the proliferation and migration of HCC cells 16 and accelerate bone metastasis of breast cancer. 21 Additionally, CENPF …

WebHepatocellular carcinoma (HCC) is one of the deadliest cancer types worldwide. The centromere proteins (CENPs) are critical for the mitosis-related protein complex and are … indian groceries online canadaWebBy searching GEO and TCGA database, we found that CENPF was upregulated in breast cancer tissues. Through RT-qPCR, CENPF was found to be upregulated in breast cancer cells. Functional experiments revealed that CENPF had positive effect on the cellular functions, including proliferation, migration and invasion. local share filesWebExpression of CENPF (hcp-1) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. ... To access cancer specific RNA and … indian groceries online germanyWebMar 3, 2024 · As one of the biomarkers for CAFs, CENPF can promote the proliferation ability of prostate cancer cells. The overexpress of CENPF could promote the proliferation ability of prostate cancer cells. In conclusion, we discuss the potential prognostic and therapeutic value of CAF-dependent pathways in prostate cancer. Introduction indian groceries in yuma azWebNomogram indicated CENPF clinical predictive value for 1-, 3-, 5-, and 7-year melanoma overall survival. Therefore, CENPF plays a vital role in the progression and … indian groceries online melbourneWebJan 1, 2024 · The full-length molecular weight of CENPF is 367 KDa and contains 3,210 amino acids [ 8 ]. In prostate cancer, CENPF has been shown to predict survival and tumor metastasis [ 9 ]. CENPF is directly associated with disease outcomes after undergoing gene amplification [ 10 ]. indian groceries online ukWebFeb 28, 2024 · It is critical to develop new effective clinical biomarkers and drug targets in RCC. Several studies have shown that centromere protein F (CENPF), a microtubule binding protein, promotes cancer progression in various types of cancer. The purpose of this study was to explore the role of CENPF in RCC. indian groceries in nj