WebMyofibrillar myopathy (MFM) is a noncommittal term that refers to a group of morphologically homogeneous, but genetically heterogeneous chronic neuromuscular disorders. The morphologic changes in skeletal muscle in MFM result from disintegration of the sarcomeric Z disc and the myofibrils, followed by abnormal ectopic accumulation of … WebJun 29, 2024 · Disease Overview. Myofibrillar myopathies are a group of rare genetic neuromuscular disorders that may be diagnosed in childhood but most often appear after 40 years of age. These conditions are highly variable but are characterized by a slowly progressive muscle weakness that can involve skeletal muscle (muscles that function to …
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WebMy-Otome (舞-乙HiME, Mai-Otome) is an anime series created by Sunrise.Directed by Masakazu Obara and written by Hiroyuki Yoshino, it is a spinoff of My-HiME anime series and as such My-Otome takes place in a new setting with new main characters.. The series originally premiered on TV Tokyo from October 6, 2005 to March 30, 2006. An OVA sequel … growing weeders into leaders
Myotilinopathy: refining the clinical and myopathological phenotype
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